{"id":2146,"date":"2024-05-30T00:21:01","date_gmt":"2024-05-29T16:21:01","guid":{"rendered":"https:\/\/sunshineivf.com.tw\/?p=2146"},"modified":"2025-06-12T00:22:41","modified_gmt":"2025-06-11T16:22:41","slug":"hello-world-33","status":"publish","type":"post","link":"https:\/\/sunshineivf.com.tw\/zh\/hello-world-33\/","title":{"rendered":"\u6bd4\u8f03\u8a98\u5c0e\u6392\u5375\u91dd\u5291\u4f7f\u7528 r-hFSH+hMG vs r-hFSH+r-hLH"},"content":{"rendered":"
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\u6bd4\u8f03\u8a98\u5c0e\u6392\u5375\u91dd\u5291\u4f7f\u7528 r-hFSH+hMG vs r-hFSH+r-hLH<\/div>\n
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pregnancy rate (52% vs. 53%, p=0.90),\u00a0<\/div>\n
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live birth rate (39% vs. 45%, p=0.19)\u00a0<\/div>\n
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\u7d50\u8ad6: \u8a98\u5c0e\u6392\u5375\u91dd\u5291\u61f7\u5b55\u7387\u6bd4\u8f03: r-hFSH+r-hLH \u7565\u512a\u65bcr-hFSH+hMG<\/div>\n
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Front Endocrinol (Lausanne)<\/div>\n
. 2022 Aug 15:13:931756. doi: 10.3389\/fendo.2022.931756. eCollection 2022.<\/div>\n
A retrospective, matched case-control study of recombinant LH versus hMG supplementation on FSH during controlled ovarian hyperstimulation in theGnRH-antagonist protocol<\/div>\n
Background: The role of luteinizing hormone (LH) in controlled ovarian hyperstimulation (COH) requires more evidence for its efficacy. Severalstudies compared recombinant human LH (r-hLH) or human menopausal gonadotropin (hMG) in combination with recombinant human follicle-stimulatinghormone (r-hFSH) but lack the results with GnRH-antagonist protocol and in Asians.<\/div>\n
Methods: This is a retrospective, single-center study inspecting women receiving GnRH antagonist protocol and r-hFSH+hMG or r-hFSH+r-hLH regimen forover five days for COH in the in vitro fertilization (IVF)\/intracytoplasmic sperm injection (ICSI) cycle in Taiwan from 2013 to 2018. The outcomes of IVF\/ICSI cycles were analyzed after propensity score matching between the two groups. A subgroup analysis was conducted in cycles in which women underwenttheir first embryo transfer (ET), including fresh ET and frozen ET (FET).<\/div>\n
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Results: With a total of 503 cycles, the results revealed that the r-hFSH+r-hLH group performed better in terms of numbers of oocytes retrieved (r-hFSH+hMG vs. r-hFSH+r-hLH, 11.7 vs. 13.7, p=0.014), mature oocytes (8.7 vs. 10.9, p=0.001), and fertilized oocytes (8.3 vs. 9.8, p=0.022), while otheroutcomes were comparable. The analysis of first ET cycles also showed similar trends. Although the implantation rate (39% vs. 43%, p=0.37),pregnancy rate (52% vs. 53%, p=0.90), and live birth rate (39% vs. 45%, p=0.19) were not significantly different, the miscarriage ratewas higher in the r-hFSH+hMG group than the r-hFSH+r-hLH group (26% vs. 15%, p<0.05) in first ET cycles. The cumulative pregnancy rate wassignificantly higher in the r-hFSH+r-hLH group (53% vs. 64%, p=0.02). No significant difference in rates of ovarian hyperstimulation syndrome (OHSS) was observed.<\/div>\n
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Conclusion: The results support the hypothesis that the treatment of r-hLH+r-hFSH improves COH clinical outcomes in the IVF\/ICSI cycle.<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

\u6bd4\u8f03\u8a98\u5c0e\u6392\u5375\u91dd\u5291\u4f7f\u7528 r-hFSH+hMG\u00a0 \u00a0vs\u00a0 r-hFSH+r-hLH \u00a0 pregnancy ra […]<\/p>\n","protected":false},"author":1,"featured_media":1952,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[14,12],"tags":[],"class_list":["post-2146","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-14","category-12"],"_links":{"self":[{"href":"https:\/\/sunshineivf.com.tw\/zh\/wp-json\/wp\/v2\/posts\/2146","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sunshineivf.com.tw\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sunshineivf.com.tw\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sunshineivf.com.tw\/zh\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/sunshineivf.com.tw\/zh\/wp-json\/wp\/v2\/comments?post=2146"}],"version-history":[{"count":4,"href":"https:\/\/sunshineivf.com.tw\/zh\/wp-json\/wp\/v2\/posts\/2146\/revisions"}],"predecessor-version":[{"id":2150,"href":"https:\/\/sunshineivf.com.tw\/zh\/wp-json\/wp\/v2\/posts\/2146\/revisions\/2150"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sunshineivf.com.tw\/zh\/wp-json\/wp\/v2\/media\/1952"}],"wp:attachment":[{"href":"https:\/\/sunshineivf.com.tw\/zh\/wp-json\/wp\/v2\/media?parent=2146"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sunshineivf.com.tw\/zh\/wp-json\/wp\/v2\/categories?post=2146"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sunshineivf.com.tw\/zh\/wp-json\/wp\/v2\/tags?post=2146"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}