Spermatozoa head shape is related to the following factors

1. acrosome formation 

2. proacrosomal vesicles Proacrosomal vesicles (PAV) 

3. manchette 

4. perinuclear theca Perinuclear membrane (PT)

5. chromatin condensation 

6. linker of nucleoskeleton

7. cytoskeleton complex (LINC) complexes 

8. 'histone-to-protamine (HTP) transition' Histone-to-protamine (HTP) transition

 

Normalization of spermatozoa head morphology correlates with ICSI results