1. Compared with the traditional observation of embryos to select embryos by the appearance of division and the presence or absence of fragments, Time-lapse can also provide information on the dynamics of embryo division.
2. The time point of early embryonic cell division is from the time of fertilization to the time of division into 2 cells (t2), 3 cells (t3), 4 cells (t4), 5 cells (t5), and 8 cells (t8) according to the number of dividing cells, and the synchronization of embryonic cell division is the time interval between the observation of the embryonic cells changing from 3 to 4 cells (s2=t4-t3), and the cell division cycle of embryonic cells is the time of the second cycle of cell division (cc2). The cell division cycle of embryonic cells is the time of the second cycle of cell division (cc2).
3. According to research, the above time points are particularly valuable as a reference for the quality of embryos. By comparing the differences in the developmental process of successfully implanted and unsuccessfully implanted embryos, the time point with the highest implantation rate is standardized.
4. Studies have shown that the implantation and pregnancy rates of embryos selected by this standard are twice as high as those of conventional fixed-time observations.
5. Therefore, the data presented by Time-lapse can be used as a reference basis for observing the quality of embryos, so as to make up for the insufficiency of observing the appearance of embryos at a fixed time in the past. In recent years, this technology has been widely used in the observation of embryo culture. Through time-lapse video, the entire growth process of the embryo can be viewed, which can help clinicians to select high-quality and healthy embryos for implantation to enhance the pregnancy rate.
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