大部分染色體異常是單一染色體異常(45 or 47染色體)

 

45染色體異常 多於 47染色體異常

 

較多染色體異常來源母系染色體

 

大部分單一染色體異常源自受孕之前之減數分裂異常

 

3個染色體aneuploidy源自受孕後有絲分裂異常

 

母系染色體異常多源自減數分裂

 

父系染色體異常多源自有絲分裂

 

 

 

Single aneuploidy was the most common type in both D3 and D5/6 embryos

 

a prevalence of single monosomy over single trisomy (n = 408, P < 0.0001, binomial test) in cleavage embryos

 

the parental origin of aneuploidy was mainly maternal, demonstrating at least a 2-fold increase in the number of affected maternal chromosomes in bothmonosomies and trisomies