自然週期vs誘導排卵 誘導排卵並不明顯提高胚胎染色體異常率 

自然週期vs誘導排卵 胚胎異常率均隨女性年齡而增加， 

自然週期vs誘導排卵 整倍體囊胚的植入率相同。

誘導排卵對胚胎非整倍體風險或胚胎生殖潛力沒有明顯副作用。

• Embryonic aneuploidy rates are equivalent in natural cycles and gonadotropin-stimulated cycles

• Aneuploidy rates were equivalent in unstimulated and stimulated IVF cycles. 

• The prevalence of aneuploidy in natural cycles increased with the age of the female partner in a manner identical to that seen in stimulatedIVF cycles. 

• Implantation rates of euploid blastocysts were equivalent in natural and stimulated IVF cycles.

• No measurable toxic effect of gonadotropin administration on aneuploidy risk or embryonic reproductive potential. 

 

 

• The overall sustained implantation rate (SIR) did not differ for patients in the natural cycle group (60.0%) as compared tosuperovulatory controls (63.8%)

• Patients less than 35 years of age had an SIR of 61.7% in the natural cycle group versus 66.5% in the control group (P=.45). 

• There were no differences in SIR between patients that were 35 to 37 years of age in natural cycle (53.3%) versus gonadotropin controlcycle patients (62.9%, P=.52). 

• Patients between the ages of 38 and 40 had SIR of 69.2% and 60.2%, in study and control groups, respectively (P=.65). 

• The SIR similarly did not vary for patients ages 41–42 in the natural cycle group and the superovulatory control group (33.3% vs. 61.4%, P=.33), or greater than 42 years of age (50.0% vs. 50.0%, P>.99).