This study evaluated the potential viability of embryos with low chimerism levels (< 50%).
Studies have shown that chimeric embryos can develop into healthy babies with different levels or types of chimerism.
No significant differences were observed between babies transferred with whole and chimeric blastocysts.
If the patient does not have a whole embryo, chimeric embryos can be transferred, which have the potential to implant and develop into a healthy baby with a whole ploidy.
This study will be valuable for consulting on clinical outcomes after single chimeric embryo transfer.
J Assist Reprod Genet
. 2020 Sep;37(9):2305-2313. doi: 10.1007/s10815-020-01876-6. Epub 2020 Jul 4. Healthy live births from transfer of low-mosaicism embryos after preimplantation genetic testing for aneuploidy
This study evaluated the potential viability of embryos with low mosaicism level (< 50%) by comparing the clinical outcomes of single mosaic versus euploid blastocyst transfer.
Our study indicated that mosaic embryos can develop into euploid healthy infants with various levels or types of mosaicism.
No significant difference was observed between infants from euploid and mosaic blastocyst transfers.
If patients have no euploid embryos, mosaic embryos can be transferred as they have potential for implantation and development into euploid healthy If patients have no euploid embryos, mosaic embryos can be transferred as they have potential for implantation and development into euploid healthy infants.
This study is invaluable for counseling clinical results after single mosaic embryo transfers.